Binding of f-PIP, a pyrrole- and imidazole-containing triamide, to the inverted CCAAT box-2 of the topoisomerase IIα promoter and modulation of gene expression in cells-Reference-Cited by-同舟云学术

Binding of f-PIP, a pyrrole- and imidazole-containing triamide, to the inverted CCAAT box-2 of the topoisomerase IIα promoter and modulation of gene expression in cells

Published:2006-12 Issue:24 Volume:16 Page:6161-6164
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Le N. Minh,Sielaff Alan M.,Cooper Amanda J.,Mackay Hilary,Brown Toni,Kotecha Minal,O’Hare Caroline,Hochhauser Daniel,Lee Moses,Hartley John A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. Binding modes of distamycin A with d(CGCAAATTTGCG)2 determined by two-dimensional NMR

2. Structural characterization of a 2:1 distamycin A.d(CGCAAATTGGC) complex by two-dimensional NMR.

3. Design and binding of a distamycin A analog to d(CGCAAGTTGGC).cntdot.d(GCCAACTTGCG): synthesis, NMR studies, and implications for the design of sequence-specific minor groove binding oligopeptides

4. Molecular recognition of DNA by small molecules

5. Recognition of the DNA minor groove by pyrrole-imidazole polyamides

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1. Effects of N-terminus modified Hx-amides on DNA binding affinity, sequence specificity, cellular uptake, and gene expression;Bioorganic & Medicinal Chemistry Letters;2021-09

2. Mixed-ligand ruthenium(II) complexes capable of hydrogen-bonding interactions with DNA: DNA binding, nuclease activity, cytotoxicity, and topoisomerase inhibition;Polyhedron;2017-11

3. Modulation of topoisomerase IIα expression and chemosensitivity through targeted inhibition of NF-Y:DNA binding by a diamino p-anisyl-benzimidazole (Hx) polyamide;Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms;2017-05

4. Nuclear Localization and Gene Expression Modulation by a Fluorescent Sequence-Selective p-Anisyl-benzimidazolecarboxamido Imidazole-Pyrrole Polyamide;Chemistry & Biology;2015-07

5. Therapeutic Agents Based on DNA Sequence Specific Binding;Current Topics in Medicinal Chemistry;2015-05-08