Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines-Reference-Cited by-同舟云学术

Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines

Published:2008-05 Issue:9 Volume:18 Page:2776-2780
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Bardelle Catherine,Cross Darren,Davenport Sara,Kettle Jason G.,Ko Eun Jung,Leach Andrew G.,Mortlock Andrew,Read Jon,Roberts Nicola J.,Robins Peter,Williams Emma J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Mechanisms and functions of eph and ephrin signalling

2. The role of ephrins and Eph receptors in cancer

3. Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis

4. EphB4 Expression and Biological Significance in Prostate Cancer

5. Eph Receptor Tyrosine Kinases in Tumor and Tumor Microenvironment

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