Design and synthesis of a novel series of (1′ S ,2 R ,4′ S )-3 H -4′-azaspiro[benzo[4,5]imidazo[2,1- b ]oxazole-2,2′-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor-Reference-Cited by-同舟云学术

Design and synthesis of a novel series of (1′ S ,2 R ,4′ S )-3 H -4′-azaspiro[benzo[4,5]imidazo[2,1- b ]oxazole-2,2′-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor

Published:2017-11 Issue:22 Volume:27 Page:5002-5005
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Cook James,Zusi F. Christopher,Hill Matthew D.,Fang Haiquan,Pearce Bradley,Park Hyunsoo,Gallagher Lizbeth,McDonald Ivar M.,Bristow Linda,Macor John E.,Olson Richard E.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference35 articles.

1. Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia

2. Neurocognitive Deficits and Functional Outcome in Schizophrenia: Are We Measuring the "Right Stuff"?

3. Neurocognitive and Social Functioning in Schizophrenia

4. What are the functional consequences of neurocognitive deficits in schizophrenia?

5. Convergence of cognitive and adaptive decline in late-life schizophrenia

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