Fragment-based design, synthesis, biological evaluation, and SAR of 1 H -benzo[ d ]imidazol-2-yl)-1 H -indazol derivatives as potent PDK1 inhibitors-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Fragment-based design, synthesis, biological evaluation, and SAR of 1 H -benzo[ d ]imidazol-2-yl)-1 H -indazol derivatives as potent PDK1 inhibitors

Published:2017-12 Issue:24 Volume:27 Page:5473-5480
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chen Ting,Sorna Venkataswamy,Choi Susie,Call Lee,Bearss Jared,Carpenter Kent,Warner Steven L.,Sharma Sunil,Bearss David J.,Vankayalapati Hariprasad

Funder

NCI

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. Targeting PDK1 in Cancer

2. Small-Molecule Inhibitors of PDK1

3. From fragment to clinical candidate—a historical perspective

4. Recent Developments in Fragment-Based Drug Discovery

5. Glide: A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification and evolution of PDK-1-like involving lamprey innate immunity;Molecular Immunology;2024-08

2. Off-target pharmacological activity at various kinases: Potential functional and pathological side effects;Journal of Pharmacological and Toxicological Methods;2023-09

3. Fluorinated Cycloalkyl Building Blocks for Drug Discovery;ChemMedChem;2022-10-05

4. Fragment hopping protocol for the design of small-molecule protein–protein interaction inhibitors;Bioorganic & Medicinal Chemistry;2022-09

5. Fragment-to-lead tailored in silico design;Drug Discovery Today: Technologies;2021-12

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3