Preparation of 5′-deoxy-5′-amino-5′- C -methyl adenosine derivatives and their activity against DOT1L-Reference-Cited by-同舟云学术

Preparation of 5′-deoxy-5′-amino-5′- C -methyl adenosine derivatives and their activity against DOT1L

Published:2017-11 Issue:22 Volume:27 Page:4960-4963
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Liu Tongchao,Xie Wuchen,Li Cong,Ren Huanming,Mao Yudong,Chen Guohua,Cheng Maosheng,Zhao Dongmei,Shen Jingkang,Li Jia,Zhou Yubo,Xiong Bing,Chen Yue-Lei

Funder

National Natural Science Foundation of China

Key New Drug Creation and Manufacturing Program

Chinese Academy of Sciences

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. Reaction intermediate analogues as bisubstrate inhibitors of pantothenate synthetase

2. Synthesis and Pharmacokinetic Evaluation of Siderophore Biosynthesis Inhibitors for Mycobacterium tuberculosis

3. Synthesis and evaluation of protein arginine N-methyltransferase inhibitors designed to simultaneously occupy both substrate binding sites

4. Facile synthesis of covalent probes to capture enzymatic intermediates during E1 enzyme catalysis

5. Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis

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