Synthesis and evaluation of pyrido-thieno-pyrimidines as potent and selective Cdc7 kinase inhibitors-Reference-Cited by-同舟云学术

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Synthesis and evaluation of pyrido-thieno-pyrimidines as potent and selective Cdc7 kinase inhibitors

Published:2009-01 Issue:2 Volume:19 Page:319-323
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Zhao Chunlin,Tovar Christian,Yin Xuefeng,Xu Qui,Todorov Ivan T.,Vassilev Lyubomir T.,Chen Li

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

2. A Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G 1 /S Transition in Mammalian Cells

3. Cdc7p-Dbf4p becomes famous in the cell cycle

4. Initiating DNA synthesis: from recruiting to activating the MCM complex

5. Drf1, a novel regulatory subunit for human Cdc7 kinase

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1. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells;Bioorganic Chemistry;2021-10

2. Synthesis of Biologically Active Heterocycles via a Domino Sequence Involving an SN2/Thorpe–Ziegler Reaction Step;Synthesis;2021-06-10

3. Unusual Oxidative Dimerization in the 3-Aminothieno[2,3-b]pyridine-2-carboxamide Series;ACS Omega;2021-05-28

4. Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor Agent;Journal of Medicinal Chemistry;2020-01-02

5. Medicinal Attributes of Thienopyrimidine Based Scaffold Targeting Tyrosine Kinases and Their Potential Anticancer Activities;Archiv der Pharmazie;2017-10-13

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