Discovery of GSK345931A: An EP1 receptor antagonist with efficacy in preclinical models of inflammatory pain-Reference-Cited by-同舟云学术

Discovery of GSK345931A: An EP1 receptor antagonist with efficacy in preclinical models of inflammatory pain

Published:2009-01 Issue:2 Volume:19 Page:497-501
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hall Adrian,Brown Susan H.,Budd Christopher,Clayton Nicholas M.,Giblin Gerard M.P.,Goldsmith Paul,Hayhow Thomas G.,Hurst David N.,Naylor Alan,Anthony Rawlings D.,Scoccitti Tiziana,Wilson Alexander W.,Winchester Wendy J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Prostaglandin E synthase

2. Microsomal Prostaglandin E Synthase-1 Is a Major Terminal Synthase That Is Selectively Up-Regulated During Cyclooxygenase-2-Dependent Prostaglandin E2 Production in the Rat Adjuvant-Induced Arthritis Model

3. Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase

4. Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Prostaglandin E2 in the Tumor Microenvironment, a Convoluted Affair Mediated by EP Receptors 2 and 4;Pharmacological Reviews;2024-03-04

2. An easy and convenient approach to novel diarypyrrole-2-carbaldehydes;Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry;2023-08-24

3. Prostaglandin E2 receptors and their role in gastrointestinal motility – Potential therapeutic targets;Prostaglandins & Other Lipid Mediators;2021-02

4. Prostaglandin E2 Induces Skin Aging via E-Prostanoid 1 in Normal Human Dermal Fibroblasts;International Journal of Molecular Sciences;2019-11-07

5. Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair;Annals of Biomedical Engineering;2019-04-12