1. For ROR1 expression levels and ROR1 therapies in clinical trials, please see the following review articles and references therein: a) Menck K.; Heinrichs S.; Baden C.; Bleckmann A.; The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic Intervention. Cells 2021, 10, 142, 1-3https://doi.org/10.3390/cells10010142. b) Zhao, Y.; Zhang, D.; Guo, Y.; Lu, B.; Zhao, Z., J.; Xu, X.; Chen, Y. Tyrosine Kinase ROR1 as a Target for Anti-Cancer Therapies, Frontiers in Oncology, doi: 10.3389/fonc.2021.680834. c) Kamrania, A.; Mehdizadehc, A.; Ahmadie, M.; Aghebati-Malekif, L.; Mehdi, Y. Therapeutic approaches for targeting receptor tyrosine kinase like orphan receptor1 in cancer cells. Expert Opinion on Therapeutic Targets 2019, 23, 447-456. https://doi.org/10.1080/14728222.2019.1602608. d) Aghebati-Maleki, L; Shabani, M.; Baradaran, B.; Motallebnezhad, M.; Majidi, J.; Yousefi, M. Receptor tyrosine kinase-like orphan receptor 1 (ROR-1): An emerging target for diagnosis and therapy of chronic lymphocytic leukemia. Biomedicine & Pharmacotherapy 2017, 88, 814-822. https://doi.org/10.1016/j.biopha.2017.01.070. e) Karvonen, H.; Niininen, W.; Murumagi, A.; Ungureanu, Targeting ROR1 identifies new treatment strategies in hematological cancers. Biochemical Society Transactions 2017, 45, 457-464. https://doi.org/10.1042/BST20160272. f) ROR-family receptor tyrosine kinases. Stricker, S.; Rauschenberger, V.; Schambony, A. Current Topics in Developmental Biology 2017, 123, 105-142. https://doi.org/10.1016/bs.ctdb.2016.09.003. g) Shabani, M.; Naseri, J.; Shokri, F. Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy. Expert Opinion on Therapeutic Targets 2015, 19, 941-955. https://doi.org/10.1517/14728222.2015.1025753. h) Hojjat-Farsangi, M.; Moshfegh, A.; Daneshmanesh, A. H.; Khan, Abdul S.; Mikaelsson, E.; Oesterborg, A.; Mellstedt, H. The receptor tyrosine kinase ROR1 - An oncofetal antigen for targeted cancer therapy. Seminars in Cancer Biology 2014, 29, 21-3https://doi.org/10.1016/j.semcancer.2014.07.005. i) Borcherding, N.; Kusner, D.; Liu, G.-H.; Zhang, W. ROR1, an embryonic protein with an emerging role in cancer biology. Protein & Cell 2014, 5, 496-502. https://doi.org/10.1007/s13238-014-0059-7. j) Bergami, P. L. The role of Ror1 receptor in cancer. Acta Bioquimica Clinica Latinoamericana 2011, 45, 665-668. k) Forrester, W. C. The Ror receptor tyrosine kinase family. Cellular and Molecular Life Sciences 2002, 59, 83-96. https://doi.org/10.1007/s00018-002-8407-9.
2. Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues;Balakrishnan;Clin Cancer Res,2017
3. The Onco-Embryonic Antigen ROR1 is Expressed by a Variety of Human Cancers;Zhang;Am J Pathol,2012
4. ROR1 is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth;Zhang;PLoS One,2012
5. Glucocorticoids promote breast cancer metastasis