Syntheses and SAR studies of 4-(heteroarylpiperdin-1-yl-methyl)-pyrrolidin-1-yl-acetic acid antagonists of the human CCR5 chemokine receptor-Reference-Cited by-同舟云学术

Syntheses and SAR studies of 4-(heteroarylpiperdin-1-yl-methyl)-pyrrolidin-1-yl-acetic acid antagonists of the human CCR5 chemokine receptor

Published:2004-07 Issue:13 Volume:14 Page:3419-3424
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Shankaran K.,Donnelly Karla L.,Shah Shrenik K.,Guthikonda Ravindra N.,MacCoss Malcolm,Mills Sander G.,Gould Sandra L.,Malkowitz Lorraine,Siciliano Salvatore J.,Springer Martin S.,Carella Anthony,Carver Gwen,Hazuda Daria,Holmes Karen,Kessler Joseph,Lineberger Janet,Miller Michael D.,Emini Emilio A.,Schleif William A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference36 articles.

1. Chemokine Receptors and Chemokines in HIV Infection

2. Chemokine Receptors As HIV Co-Receptors: Targets for Therapeutic Intervention in AIDS

3. Opportunities for novel therapeutic agents acting at chemokine receptors

4. Recent developments in modulating chemokine networks

5. Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 + T Cells

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