Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluation-Reference-Cited by-同舟云学术

Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluation

Published:2009-08 Issue:15 Volume:19 Page:4159-4166
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Uto Yoshikazu,Ogata Tsuneaki,Kiyotsuka Yohei,Miyazawa Yuriko,Ueno Yuko,Kurata Hitoshi,Deguchi Tsuneo,Yamada Makiko,Watanabe Nobuaki,Takagi Toshiyuki,Wakimoto Satoko,Okuyama Ryo,Konishi Masahiro,Kurikawa Nobuya,Kono Keita,Osumi Jun

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Stearoyl-CoA desaturase as a new drug target for obesity treatment

2. Recent insights into stearoyl-CoA desaturase-1

3. The Biosynthesis of Hepatic Cholesterol Esters and Triglycerides Is Impaired in Mice with a Disruption of the Gene for Stearoyl-CoA Desaturase 1

4. Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism

5. Stearoyl-CoA desaturase: a new therapeutic target of liver steatosis

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