The P1 N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin-Reference-Cited by-同舟云学术

The P1 N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin

Published:2009-08 Issue:16 Volume:19 Page:4863-4867
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Yamaguchi Yasuchika,Menear Keith,Cohen Nissim-Claude,Mah Robert,Cumin Frédéric,Schnell Christian,Wood Jeanette M.,Maibaum Jürgen

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

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4. Renin inhibitors: An antihypertensive strategy on the verge of reality

5. Renin inhibitors as novel treatments for cardiovascular disease

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