Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors-Reference-Cited by-同舟云学术

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Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors

Published:2009-08 Issue:15 Volume:19 Page:4228-4231
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hosoda Shinnosuke,Matsuda Daisuke,Tomoda Hiroshi,Hashimoto Mariko,Aoyama Hiroshi,Hashimoto Yuichi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3

2. Structure-Based Design of Selective Agonists for a Rickets-Associated Mutant of the Vitamin D Receptor

3. Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities

4. Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation

5. 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1

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1. Design and Synthesis of 1,3,5-Triazine Derivatives as Novel Inverse Agonists of Nuclear Retinoic Acid Receptor-Related Orphan Receptor-γ;HETEROCYCLES;2017

2. Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis;Steroids;2015-07

3. Hypercholesterolemia: Chemical Aspect of Approach;Current Medicinal Chemistry;2011-09-01

4. Novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors: a patent review;Expert Opinion on Therapeutic Patents;2011-01-10

5. Development of tryptase inhibitors derived from thalidomide;Bioorganic & Medicinal Chemistry;2010-07

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