Discovery of pyrrolopyrimidine inhibitors of Akt-Reference-Cited by-同舟云学术

Discovery of pyrrolopyrimidine inhibitors of Akt

Published:2010-10 Issue:19 Volume:20 Page:5607-5612
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Blake James F.,Kallan Nicholas C.,Xiao Dengming,Xu Rui,Bencsik Josef R.,Skelton Nicholas J.,Spencer Keith L.,Mitchell Ian S.,Woessner Richard D.,Gloor Susan L.,Risom Tyler,Gross Stefan D.,Martinson Matthew,Morales Tony H.,Vigers Guy P.A.,Brandhuber Barbara J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. The Akt/PKB pathway: molecular target for cancer drug discovery

2. Perturbations of the AKT signaling pathway in human cancer

3. Class reunion: PTEN joins the nuclear crew

4. Inhibition of PI3K/Akt Signaling: An Emerging Paradigm for Targeted Cancer Therapy

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