New synthetic route to ethynyl-dUTP: A means to avoid formation of acetyl and chloro vinyl base-modified triphosphates that could poison SELEX experiments
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference49 articles.
1. Synthesis of Base-Modified 2′-Deoxyribonucleoside Triphosphates and Their Use in Enzymatic Synthesis of Modified DNA for Applications in Bioanalysis and Chemical Biology
2. Nucleoside Triphosphates — Building Blocks for the Modification of Nucleic Acids
3. Structural Insights into the Processing of Nucleobase-Modified Nucleotides by DNA Polymerases
4. Nucleobase modification as redox DNA labelling for electrochemical detection
5. Dressed for success – applying chemistry to modulate aptamer functionality
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1. Facilitated Synthetic Access to Boronic Acid-Modified Nucleoside Triphosphates and Compatibility with Enzymatic DNA Synthesis;Synlett;2023-11-16
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5. Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker;Proceedings of the National Academy of Sciences;2020-07-06
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