Structure activity study of S-trityl-cysteamine dimethylaminopyridine derivatives as SIRT2 inhibitors: Improvement of SIRT2 binding and inhibition
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference32 articles.
1. Sirtuin chemical mechanisms;Sauve;Biochim Biophys Acta (BBA) – Proteins and Proteomics,2010
2. The human Sir2 ortholog, SIRT2, Is an NAD+-dependent tubulin deacetylase;North;Mol Cell,2003
3. An overview of Sirtuins as potential therapeutic target: structure, function and modulators;Wang;Eur J Med Chem,2019
4. Recent advances in inhibitors of sirtuin1/2: an update and perspective;Zhou;Future Med Chem,2018
5. Role of histone deacetylases and their inhibitors in cancer biology and treatment;Beumer;Curr Clin Pharmacol,2010
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