Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing-Reference-Cited by-同舟云学术

Discovery of a series of benzopyrimidodiazepinone TNK2 inhibitors via scaffold morphing

Published:2020-10 Issue:19 Volume:30 Page:127456
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Li Zhengnian,Powell Chelsea E.,Groendyke Brian J.,Gero Thomas W.,Feru Frederic,Feutrill John,Chen Bailing,Li Bin,Szabo Hilary,Gray Nathanael S.,Scott David A.^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Regulation of Ack-Family Nonreceptor Tyrosine Kinases

2. ACK1 tyrosine kinase: Targeted inhibition to block cancer cell proliferation

3. ACK1/TNK2 tyrosine kinase: molecular signaling and evolving role in cancers

4. Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis

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1. Research Progress on AKC1 and Its Small Molecule Inhibitors in Tumor Occurrence and Development;Advances in Clinical Medicine;2024

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4. ACK1 Contributes to the Pathogenesis of Inflammation and Autoimmunity by Promoting the Activation of TLR Signaling Pathways;Frontiers in Immunology;2022-05-20

5. Small Molecules Targeting Activated Cdc42-Associated Kinase 1 (ACK1/TNK2) for the Treatment of Cancers;Journal of Medicinal Chemistry;2021-11-04