Discovery of 2,6–difluorobenzyl ether series of phenyl ((R)–3–phenylpyrrolidin–3–yl)sulfones as surprisingly potent, selective and orally bioavailable RORγt inverse agonists-Reference-Cited by-同舟云学术

Discovery of 2,6–difluorobenzyl ether series of phenyl ((R)–3–phenylpyrrolidin–3–yl)sulfones as surprisingly potent, selective and orally bioavailable RORγt inverse agonists

Published:2020-10 Issue:19 Volume:30 Page:127441
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Duan James J.-W.,Jiang Bin^ORCID,Lu Zhonghui,Stachura Sylwia,Weigelt Carolyn A.,Sack John S.,Khan Javed,Ruzanov Max,Wu Dauh–Rurng,Yarde Melissa,Shen Ding–Ren,Zhao Qihong,Salter–Cid Luisa M.,Carter Percy H.,Murali Dhar T.G.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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