Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties-Reference-Cited by-同舟云学术

Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties

Published:2011-02 Issue:4 Volume:21 Page:1134-1140
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Richter Hans G.F.,Benson G.M.,Bleicher K.H.,Blum D.,Chaput E.,Clemann N.,Feng S.,Gardes C.,Grether U.,Hartman P.,Kuhn B.,Martin R.E.,Plancher J.-M.,Rudolph M.G.,Schuler F.,Taylor S.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference35 articles.

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2. Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors

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4. Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

5. Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR

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