Design and synthesis of potent Gram-negative specific LpxC inhibitors-Reference-Cited by-同舟云学术

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Design and synthesis of potent Gram-negative specific LpxC inhibitors

Published:2011-02 Issue:4 Volume:21 Page:1155-1161
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Faruk Mansoor U.,Vitharana Dilrukshi,Reddy Panduranga Adulla,Daubaras Dayna L.,McNicholas Paul,Orth Peter,Black Todd,Arshad Siddiqui M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Antibiotic resistance—the problem intensifies

2. Antibacterial resistance worldwide: causes, challenges and responses

3. Where will new antibiotics come from?

4. New (and not so new) antibacterial targets – from where and when will the novel drugs come?

5. MOLECULAR GENETICS OF MEMBRANE PHOSPHOLIPID SYNTHESIS

Cited by 42 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Small molecule LpxC inhibitors against gram-negative bacteria: Advances and future perspectives;European Journal of Medicinal Chemistry;2023-05

2. LpxC (UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase) inhibitors: A long path explored for potent drug design;International Journal of Biological Macromolecules;2023-04

3. Making a chink in their armor: Current and next-generation antimicrobial strategies against the bacterial cell envelope;Advances in Microbial Physiology;2023

4. The Complex Structure of Protein AaLpxC from Aquifex aeolicus with ACHN-975 Molecule Suggests an Inhibitory Mechanism at Atomic-Level against Gram-Negative Bacteria;Molecules;2021-03-07

5. N-Hydroxyformamide LpxC inhibitors, their in vivo efficacy in a mouse Escherichia coli infection model, and their safety in a rat hemodynamic assay;Bioorganic & Medicinal Chemistry;2020-12

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