Design, synthesis and evaluation of novel levoglucosenone derivatives as promising anticancer agents

Author:

Tsai Yi-hsuan,Borini Etichetti Carla M.,Cicetti Soledad,Girardini Javier E.,Spanevello Rolando A.ORCID,Suárez Alejandra G.,Sarotti Ariel M.ORCID

Funder

CONICET

ANPCyT

UNESCO

IUPAC

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference29 articles.

1. a) Levoglucosenone and Levoglucosans: Chemistry and Applications; Witczak, Z. J., Ed.; ATL Press: Mount Prospect, USA, 1994. b) M. B. Comba, Y. Tsai, A. M. Sarotti, M. I. Mangione, A. G. Suárez and R. A. Spanevello, Eur. J. Org. Chem., 2018:590–604. c) M. S. Miftakhov, F. A. Valeev and I. N. Gaisina, Russ. Chem. Rev., 1994;63:869-882.

2. Palladium-Catalyzed Suzuki-Miyaura, Heck and Hydroarylation Reactions on (-)-Levoglucosenone and Application to the Synthesis of Chiral γ-Butyrolactones

3. Bio-Based Chiral Amines via Aza-Michael Additions to (-)-Levoglucosenone Under Aqueous Conditions

4. A Domino Epoxide Ring-Opening Xanthate Migration Reaction: An Alternative Entry to Thiosugars

5. Joint Experimental, in Silico, and NMR Studies toward the Rational Design of Iminium-Based Organocatalyst Derived from Renewable Sources

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