[2-(4-Phenyl-4-piperidinyl)ethyl]amine based CCR5 antagonists: derivatizations at the N-terminal of the piperidine ring-Reference-Cited by-同舟云学术

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[2-(4-Phenyl-4-piperidinyl)ethyl]amine based CCR5 antagonists: derivatizations at the N-terminal of the piperidine ring

Published:2009-03 Issue:6 Volume:19 Page:1610-1613
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Duan Maosheng,Aquino Christopher,Ferris Robert,Kazmierski Wieslaw M.,Kenakin Terry,Koble Cecilia,Wheelan Pat,Watson Chris,Youngman Michael

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference8 articles.

1. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

2. Chapter 19 Small Molecule CCR5 and CXCR4-Based Viral Entry Inhibitors for Anti-HIV Therapy Currently in Development

3. The Discovery of the CCR5 Receptor Antagonist, UK-427,857, A New Agent for the Treatment of HIV Infection and AIDS

4. Discovery of Bioavailable 4,4-Disubstituted Piperidines as Potent Ligands of the Chemokine Receptor 5 and Inhibitors of the Human Immunodeficiency Virus-1

5. Dialkyltin oxide mediated addition of trimethylsilyl azide to nitriles. A novel preparation of 5-substituted tetrazols

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1. Broad-spectrum antiviral strategy: Host-targeting antivirals against emerging and re-emerging viruses;European Journal of Medicinal Chemistry;2024-02

2. Recent Progress in the Development of HIV-1 Entry Inhibitors: From Small Molecules to Potent Anti-HIV Agents;Current Topics in Medicinal Chemistry;2019-10-09

3. Structure-Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists;Journal of Medicinal Chemistry;2018-09-20

4. Recent updates for designing CCR5 antagonists as anti-retroviral agents;European Journal of Medicinal Chemistry;2018-03

5. Structural Analysis of Chemokine Receptor–Ligand Interactions;Journal of Medicinal Chemistry;2017-03-10

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