Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-α: Hit to lead studies-Reference-Cited by-同舟云学术

Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-α: Hit to lead studies

Published:2010-01 Issue:2 Volume:20 Page:636-639
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Gilbert Adam M.,Nowak Pawel,Brooijmans Natasja,Bursavich Matthew G.,Dehnhardt Christoph,Santos Efren Delos,Feldberg Larry R.,Hollander Irwin,Kim Stephen,Lombardi Sabrina,Park Kaapjoo,Venkatesan Aranapakam M.,Mallon Robert

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Synthesis and Function of 3-Phosphorylated Inositol Lipids

2. Targeting the phosphoinositide 3-kinase pathway in cancer

3. PIK3CA Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma

4. Class IA phosphoinositide 3-kinase isoforms and human tumorigenesis: implications for cancer drug discovery and development

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