Cyclization-activated prodrugs. Synthesis, reactivity and toxicity of dipeptide esters of paracetamol-Reference-Cited by-同舟云学术

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Cyclization-activated prodrugs. Synthesis, reactivity and toxicity of dipeptide esters of paracetamol

Published:2005-03 Issue:6 Volume:15 Page:1595-1598
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Santos Cledir,Mateus Maria Luísa,dos Santos Ana Paula,Moreira Rui,de Oliveira Eliandre,Gomes Paula

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. A Textbook of Drug Design and Development;Friis,1996

2. Acetaminophen-induced hepatic necrosis and renal failure

3. Synthesis, decomposition kinetics, and preliminary toxicological studies of pure N-acetyl-p-benzoquinone imine, a proposed toxic metabolite of acetaminophen

4. Molecular Aspects of Paracetamol-Induced Hepatotoxicity and its Mechanism-Based Prevention

5. Synthesis, Physical Properties, Toxicological Studies and Bioavailability of L-Pyroglutamic and L-Glutamic Acid Esters of Paracetamol as Potentially Useful Prodrugs

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1. Exploring acetaminophen prodrugs and hybrids: a review;RSC Advances;2024

2. Synthesis and Characterization of New Functionalized 1,2,3-Triazole-Based Acetaminophen Derivatives via Click Chemistry from Expired Commercial Acetaminophen Tablets;Reactions;2023-06-21

3. A Short Review on Biological Activities of Paracetamol Derivatives;International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN);2023-02-13

4. Design and synthesis of water-soluble prodrugs of rifabutin for intraveneous administration;European Journal of Medicinal Chemistry;2022-08

5. Design and Synthesis of Water-Soluble Prodrugs of Rifabutin for Intraveneous Administration;SSRN Electronic Journal;2022

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