Identification of pyrimidinyl piperazines as non-iminosugar glucocerebrosidase (GCase) pharmacological chaperones-Reference-Cited by-同舟云学术

Identification of pyrimidinyl piperazines as non-iminosugar glucocerebrosidase (GCase) pharmacological chaperones

Published:2023-02 Issue: Volume:81 Page:129130
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hoshikawa Tamaki^ORCID,Watanabe Toru,Kotake Makoto,Tiberghien Nathalie,Woo Chi-kit,Lewis Sian^ORCID,Briston Thomas^ORCID,Koglin Mumta,Staddon James M.^ORCID,Powney Ben,Schapira Anthony H.V.,Takle Andrew K.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Glucocerebrosidase: Functions in and Beyond the Lysosome

2. Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA)

3. Glucocerebrosidase-associated Parkinson disease: Pathogenic mechanisms and potential drug treatments

4. CNS, lung, and lymph node involvement in Gaucher disease type 3 after 11years of therapy: Clinical, histopathologic, and biochemical findings

5. Enzyme Replacement or Substrate Reduction? A Review of Gaucher Disease Treatment Options

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