SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide (MGCD0103)-Reference-Cited by-同舟云学术

SAR and biological evaluation of analogues of a small molecule histone deacetylase inhibitor N-(2-aminophenyl)-4-((4-(pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide (MGCD0103)

Published:2009-02 Issue:3 Volume:19 Page:644-649
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Raeppel Stéphane,Zhou Nancy,Gaudette Frédéric,Leit Silvana,Paquin Isabelle,Larouche Guillaume,Moradei Oscar,Fréchette Sylvie,Isakovic Ljubomir,Delorme Daniel,Fournel Marielle,Kalita Ann,Lu Aihua,Trachy-Bourget Marie-Claude,Yan Pu Theresa,Liu Jianhong,Rahil Jubrail,Wang James,Besterman Jeffrey M.,Murakami Koji,Li Zuomei,Vaisburg Arkadii

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Histone deacetylases and cancer

2. The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

3. HDAC Inhibition in Cancer Therapy: An Increasingly Intriguing Tale of Chemistry, Biology and Clinical Benefit

4. Histone Deacetylase Inhibitors: From Bench to Clinic

5. Histone Deacetylase Inhibitors in Cancer Therapy: New Compounds and Clinical Update of Benzamide-Type Agents

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