Expanding the structural diversity of Bcr-Abl inhibitors: Hybrid molecules based on GNF-2 and Imatinib-Reference-Cited by-同舟云学术

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Expanding the structural diversity of Bcr-Abl inhibitors: Hybrid molecules based on GNF-2 and Imatinib

Published:2015-10 Issue:19 Volume:25 Page:4164-4168
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Pan Xiaoyan,Dong Jinyun,Shao Ruili,Su Ping,Shi Yaling,Wang Jinfeng,He Langchong

Funder

Natural Science Foundation of China (NSFC)

Natural Science Basic Research Plan in Shaanxi Province of China

Fundamental Research Funds for the Central Universities

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference35 articles.

1. Chronic Myeloid Leukemia

2. BCR-ABL Tyrosine Kinase Inhibitors for Chronic Myelogenous Leukemia

3. The molecular biology of chronic myeloid leukemia

4. Signal transmission of BCR-ABL in chronic myelogenous leukemia.

5. Down-regulation of Thanatos-associated protein 11 by BCR-ABL promotes CML cell proliferation through c-Myc expression

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4. Design, synthesis, and biological evaluation of novel Bcr-AblT315I inhibitors incorporating amino acids as flexible linker;Bioorganic & Medicinal Chemistry;2021-10

5. The Discovery of Novel BCR-ABL Tyrosine Kinase Inhibitors Using a Pharmacophore Modeling and Virtual Screening Approach;Frontiers in Cell and Developmental Biology;2021-03-04

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