2,3′-Bis(1′H-indole) heterocycles: New p53/MDM2/MDMX antagonists-Reference-Cited by-同舟云学术

2,3′-Bis(1′H-indole) heterocycles: New p53/MDM2/MDMX antagonists

Published:2015-12 Issue:24 Volume:25 Page:5661-5666
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Neochoritis Constantinos G.,Wang Kan,Estrada-Ortiz Natalia,Herdtweck Eberhardt,Kubica Katarzyna,Twarda Aleksandra,Zak Krzysztof M.,Holak Tad A.,Dömling Alexander

Funder

Marie Curie FP7-Reintegration

EU European Regional Development Fund

NIH

Innovative Medicines Initiative

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference38 articles.

1. p53, guardian of the genome

2. p53, the Cellular Gatekeeper for Growth and Division

3. p53—A Natural Cancer Killer: Structural Insights and Therapeutic Concepts

4. Mdm2 promotes the rapid degradation of p53

5. MDM2 — master regulator of the p53 tumor suppressor protein

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