Identification and structure–activity relationships of substituted pyridones as inhibitors of Pim-1 kinase-Reference-Cited by-同舟云学术

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Identification and structure–activity relationships of substituted pyridones as inhibitors of Pim-1 kinase

Published:2007-03 Issue:6 Volume:17 Page:1679-1683
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Cheney I. Wayne,Yan Shunqi,Appleby Todd,Walker Heli,Vo Todd,Yao Nanhua,Hamatake Robert,Hong Zhi,Wu Jim Z.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

2. Proviral tagging in E mu-myc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2.

3. KID-1, a Protein Kinase Induced by Depolarization in Brain

4. Pim-1: A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis

5. The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias.

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