N4-Phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease-Reference-Cited by-同舟云学术

N4-Phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease

Published:2007-11 Issue:21 Volume:17 Page:5783-5789
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Huang Wenwei,Zheng Wei,Urban Daniel J.,Inglese James,Sidransky Ellen,Austin Christopher P.,Thomas Craig J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Glycosphingolipid Structure and Function in Membranes

2. Therapeutic strategies to ameliorate lysosomal storage disorders – a focus on Gaucher disease

3. The cell biology of lysosomal storage disorders

4. Gaucher Disease;Hruska,2006

5. Replacement Therapy for Inherited Enzyme Deficiency — Macrophage-Targeted Glucocerebrosidase for Gaucher's Disease

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of novel glucocerebrosidase chaperones by unexpected skeletal rearrangement reaction;Bioorganic & Medicinal Chemistry Letters;2023-11

2. 2,4,6-Tris(p-aminoanilino)-1,3,5-triazine: Synthesis and Electron Paramagnetic Resonance (EPR) Analysis;Sakarya University Journal of Science;2022-10-10

3. Efficient synthesis of unsymmetrical trisubstituted 1,3,5-triazines catalyzed by hemoglobin;Molecular Catalysis;2021-04

4. Ruthenium-catalyzed N-alkylation of amino-1,3,5-triazines using alcohols;New Journal of Chemistry;2021

5. Di- and tri-substituted s-triazine derivatives: Synthesis, characterization, anticancer activity in human breast-cancer cell lines, and developmental toxicity in zebrafish embryos;Bioorganic Chemistry;2020-01