Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors-Reference-Cited by-同舟云学术

Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors

Published:2014-02 Issue:3 Volume:24 Page:893-899
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Goto Taiji,Shiina Akiko,Murata Takeshi,Tomii Masato,Yamazaki Takanori,Yoshida Ken-ichi,Yoshino Toshiharu,Suzuki Osamu,Sogawa Yoshitaka,Mizukami Kiyoshi,Takagi Nana,Yoshitomi Tomomi,Etori Maki,Tsuchida Hiroshi,Mikkaichi Tsuyoshi,Nakao Naoki,Takahashi Mizuki,Takahashi Hisashi,Sasaki Shigeki

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

2. Phosphodiesterase-4 as a potential drug target

3. Phosphodiesterase Isozymes

4. Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and COPD

5. Keynote review: Phosphodiesterase-4 as a therapeutic target

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