Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)-Reference-Cited by-同舟云学术

Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)

Published:2014-02 Issue:3 Volume:24 Page:995-999
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Xu Lianhong,Liu Hongtao,Hong Allen,Vivian Randy,Murray Bernard P.,Callebaut Christian,Choi You-Chul,Lee Melody S.,Chau Jennifer,Tsai Luong K.,Stray Kirsten M.,Strickley Robert G.,Wang Jianhong,Tong Leah,Swaminathan Swami,Rhodes Gerry R.,Desai Manoj C.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

2. Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and Inhibitors

3. THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS*

4. Summary of information on human CYP enzymes: human P450 metabolism data

5. Using Pharmacokinetics to Optimize Antiretroviral Drug-Drug Interactions in the Treatment of Human Immunodeficiency Virus Infection

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