Novel benzoylpiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 6-[4-(2-methylbenzoyl)piperidin-1-yl]pyridazine-3-carboxylic acid (2-hydroxy-2-pyridin-3-ylethyl)amide and its plasma triglyceride-lowering effects in Zucker fatty rats-Reference-Cited by-同舟云学术

Novel benzoylpiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 6-[4-(2-methylbenzoyl)piperidin-1-yl]pyridazine-3-carboxylic acid (2-hydroxy-2-pyridin-3-ylethyl)amide and its plasma triglyceride-lowering effects in Zucker fatty rats

Published:2010-01 Issue:1 Volume:20 Page:341-345
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Uto Yoshikazu,Ogata Tsuneaki,Kiyotsuka Yohei,Ueno Yuko,Miyazawa Yuriko,Kurata Hitoshi,Deguchi Tsuneo,Watanabe Nobuaki,Konishi Masahiro,Okuyama Ryo,Kurikawa Nobuya,Takagi Toshiyuki,Wakimoto Satoko,Ohsumi Jun

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. Stearoyl-CoA desaturase as a new drug target for obesity treatment

2. Recent insights into stearoyl-CoA desaturase-1

3. Identification and Characterization of Murine SCD4, a Novel Heart-specific Stearoyl-CoA Desaturase Isoform Regulated by Leptin and Dietary Factors

4. Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates

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