Optimization of clofibrate with O-desmethyl anetholtrithione lead to a novel hypolipidemia compound with hepatoprotective effect-Reference-Cited by-同舟云学术

Optimization of clofibrate with O-desmethyl anetholtrithione lead to a novel hypolipidemia compound with hepatoprotective effect

Published:2022-09 Issue: Volume:72 Page:128844
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Liu Haitao,Zhang Panpan,Ge Xiaoxiao,Wu Qiong,Han Chuchu,Zhang Linyang,Hua Yuxin,Zhang Yuxuan,Liu Jiping,Shi Yongheng,Wang Bin,Wang Xiaoping,Wang Wei,Jiang Yi,Zhang Huawei,Deng Chong,Xie Yundong,Liu Ying,He Shipeng

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Hypertriglyceridemia: new approaches in management and treatment

2. PPAR-alpha: A Key to the Mechanism of Hepatoprotection by Clofibrate

3. Peroxisome Proliferator-Activated Receptor Alpha-Null Mice Lack Resistance to Acetaminophen Hepatotoxicity following Clofibrate Exposure

4. Difference between species in response to a 3,5‐dichloropyridyloxyphenoxy compound: Induction of cytochrome P‐450 and/or peroxisome proliferation†

5. Mechanism of clofibrate hepatotoxicity: mitochondrial damage and oxidative stress in hepatocytes

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1. Structural simplification and ester bond flipping lead to bis-benzodioxole derivatives as potential hypolipidemic and hepatoprotective agent;Medicinal Chemistry Research;2024-05

2. Optimization of clofibrate with natural product sesamol for reducing liver injury induced by acetaminophen;Medicinal Chemistry Research;2022-11-01