Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors-Reference-Cited by-同舟云学术

Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors

Published:2005-02 Issue:4 Volume:15 Page:905-909
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Zhao Zhijian,Leister William H.,Robinson Ronald G.,Barnett Stanley F.,Defeo-Jones Deborah,Jones Raymond E.,Hartman George D.,Huff Joel R.,Huber Hans E.,Duggan Mark E.,Lindsley Craig W.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Emerging targets in the AKT pathway for treatment of androgen-independent prostatic adenocarcinoma

2. The protein kinase B/Akt signalling pathway in human malignancy

3. Targeting Serine / Threonine Protein Kinase B / Akt and Cell-cycle Checkpoint Kinases for Treating Cancer

4. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

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