Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells-Reference-Cited by-同舟云学术

Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells

Published:2009-09 Issue:17 Volume:19 Page:4924-4928
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Allen John G.,Lee Matthew R.,Han Chun-Ya E.,Scherrer Jon,Flynn Shaun,Boucher Christy,Zhao Huilin,O’Connor Anne B.,Roveto Philip,Bauer David,Graceffa Russell,Richards William G.,Babij Philip

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Building bone to reverse osteoporosis and repair fractures

2. Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

3. RAFTK/Pyk2-mediated cellular signalling

4. PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase.

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