Use of molecular modeling aided design to dial out hERG liability in adenosine A2A receptor antagonists-Reference-Cited by-同舟云学术

Use of molecular modeling aided design to dial out hERG liability in adenosine A2A receptor antagonists

Published:2015-08 Issue:15 Volume:25 Page:2958-2962
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Deng Qiaolin,Lim Yeon-Hee,Anand Rajan,Yu Younong,Kim Jae-hun,Zhou Wei,Zheng Junying,Tempest Paul,Levorse Dorothy,Zhang Xiaoping,Greene Scott,Mullins Deborra,Culberson Chris,Sherborne Brad,Parker Eric M.,Stamford Andrew,Ali Amjad

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Adenosine A2A Receptor as a Drug Discovery Target

2. ACTIONS OF ADENOSINE AT ITS RECEPTORS IN THE CNS: Insights from Knockouts and Drugs

3. Adenosine A2A Receptor Antagonists and Parkinson’s Disease

4. Predictive in silico modeling for hERG channel blockers

5. A structural basis for drug-induced long QT syndrome

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