Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1
Author:
Funder
Cancer Research UK
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference41 articles.
1. Uniprot: Human ERAP1 Q9NZO8, Human ERAP2 Q6P179.
2. How ERAP1 and ERAP2 shape the peptidomes of disease-associated MHC-I proteins;López de Castro;Front Immunol.,2018
3. Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1;Giastas;Proc Natl Acad Sci USA.,2019
4. The urgent need to recover MHC class I in cancers for effective immunotherapy;Garrido;Curr Opin Immunol.,2016
5. ERAP1: a potential therapeutic target for a myriad of diseases;Reeves;Expert Opin Ther Targets.,2020
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2. Diastereoselective Synthesis of Phosphinic Dipeptide Isosteres: Domino Chirality Transfer during a Stereocontrolled P-Michael Reaction;Organic Letters;2023-09-05
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