Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one-Reference-Cited by-同舟云学术

Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one

Published:2013-11 Issue:21 Volume:23 Page:5829-5832
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Tang Haifeng,de Jesus Reynald K.,Walsh Shawn P.,Zhu Yuping,Yan Yan,Priest Birgit T.,Swensen Andrew M.,Alonso-Galicia Magdalena,Felix John P.,Brochu Richard M.,Bailey Timothy,Thomas-Fowlkes Brande,Zhou Xiaoyan,Pai Lee-Yuh,Hampton Caryn,Hernandez Melba,Owens Karen,Roy Sophie,Kaczorowski Gregory J.,Yang Lihu,Garcia Maria L.,Pasternak Alexander

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. Cloning and expression of an inwardly rectifying ATP-regulated potassium channel

2. Molecular Diversity and Regulation of Renal Potassium Channels

3. Pharmacotyping of hypokalaemic salt-losing tubular disorders

4. Renal potassium channels: recent developments

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