Structure-based design and synthesis of bicyclic fused-pyridines as MEK inhibitors-Reference-Cited by-同舟云学术

Structure-based design and synthesis of bicyclic fused-pyridines as MEK inhibitors

Published:2014-06 Issue:11 Volume:24 Page:2555-2559
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lu Hejun,Tu Wangyang,Fei Hongbo,Xu Guoji,Hu Qiyue,Zhang Lei,Lin Bing,Yuan Jijun,Yin Junzhao,Gong Aishen,Wan Mimi,Wang Dan,Zhu Xiaoyan,Feng Jun,Wang Qian,Sun Piaoyang

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. Comprehensive Predictive Biomarker Analysis for MEK Inhibitor GSK1120212

2. MEK inhibitors: a patent review 2008 – 2010

3. Intrinsic resistance to selumetinib, a selective inhibitor of MEK1/2, by cAMP-dependent protein kinase A activation in human lung and colorectal cancer cells

4. Novel mitogen-activated protein kinase kinase inhibitors

5. The Therapeutic Promise of Anti-Cancer Drugs Against the Ras/Raf/MEK/ERK Pathway

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