Discovery of XL888: A novel tropane-derived small molecule inhibitor of HSP90-Reference-Cited by-同舟云学术

Discovery of XL888: A novel tropane-derived small molecule inhibitor of HSP90

Published:2012-09 Issue:17 Volume:22 Page:5396-5404
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Bussenius Joerg,Blazey Charles M.,Aay Naing,Anand Neel K.,Arcalas Arlyn,Baik TaeGon,Bowles Owen J.,Buhr Chris A.,Costanzo Simona,Curtis Jeffrey K.,DeFina Steven C.,Dubenko Larisa,Heuer Timothy S.,Huang Ping,Jaeger Christopher,Joshi Anagha,Kennedy Abigail R.,Kim Angie I.,Lara Katherine,Lee Jae,Li Jonathan,Lougheed Julie C.,Ma Sunghoon,Malek Shiva,Manalo Jean-Claire L.,Martini Jean-Francois,McGrath Garth,Nicoll Monique,Nuss John M.,Pack Michael,Peto Csaba J.,Tsang Tsze H.,Wang Longcheng,Womble Scott W.,Yakes Michael,Zhang Wentao,Rice Kenneth D.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference38 articles.

1. Molecular Chaperones and Protein Quality Control

2. Experimental investigation of protein folding and misfolding

3. The 90-kDa Molecular Chaperone Family

4. Hsp70 and Hsp90—a relay team for protein folding

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