Synthesis and DNA binding properties of 1-(3-aminopropyl)-imidazole-containing triamide f-Im∗PyIm: A novel diamino polyamide designed to target 5′-ACGCGT-3′-Reference-Cited by-同舟云学术

Synthesis and DNA binding properties of 1-(3-aminopropyl)-imidazole-containing triamide f-Im∗PyIm: A novel diamino polyamide designed to target 5′-ACGCGT-3′

Published:2012-09 Issue:18 Volume:22 Page:5898-5902
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Satam Vijay,Babu Balaji,Porte Alexander,Savagian Mia,Lee Megan,Smeltzer Thomas,Liu Yang,Ramos Joseph,David Wilson W.,Lin Shicai,Kiakos Kostantinos,Hartley John A.,Lee Moses

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference49 articles.

1. Structure of the side-by-side binding of distamycin to d(GTATATAC)2

2. Structural characterization of a 2:1 distamycin A.d(CGCAAATTGGC) complex by two-dimensional NMR.

3. Binding modes of distamycin A with d(CGCAAATTTGCG)2 determined by two-dimensional NMR

4. Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia

5. Extending the recognition site of designed minor groove binding molecules

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthetic DNA Binding Assembly: Architecture, Application and Perspectives;Springer Theses;2020

2. Modulation of topoisomerase IIα expression and chemosensitivity through targeted inhibition of NF-Y:DNA binding by a diamino p-anisyl-benzimidazole (Hx) polyamide;Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms;2017-05

3. AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamide;Bioorganic & Medicinal Chemistry Letters;2015-09

4. Dynamic hydrogen bonding and DNA flexibility in minor groove binders: molecular dynamics simulation of the polyamide f-ImPyIm bound to the Mlu1 (MCB) sequence 5′-ACGCGT-3′ in 2:1 motif;Journal of Molecular Recognition;2015-02-24

5. Design, synthesis, and DNA binding characteristics of a group of orthogonally positioned diamino, N-formamido, pyrrole- and imidazole-containing polyamides;Bioorganic & Medicinal Chemistry;2013-07