Scaffold hopping towards potent and selective JAK3 inhibitors: Discovery of novel C-5 substituted pyrrolopyrazines-Reference-Cited by-同舟云学术

Scaffold hopping towards potent and selective JAK3 inhibitors: Discovery of novel C-5 substituted pyrrolopyrazines

Published:2014-11 Issue:21 Volume:24 Page:4969-4975
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

de Vicente Javier,Lemoine Remy,Bartlett Mark,Hermann Johannes C.,Hekmat-Nejad Mohammad,Henningsen Robert,Jin Sue,Kuglstatter Andreas,Li Hongju,Lovey Allen J.,Menke John,Niu Linghao,Patel Vaishali,Petersen Ann,Setti Lina,Shao Ada,Tivitmahaisoon Parcharee,Vu Minh Diem,Soth Michael

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference33 articles.

1. Jak and Syk: Emerging their relevance to the treatment of inflammatory diseases

2. Jaks, STATs, Cytokine Signal Transduction, and Immunoregulation: Are We There Yet?

3. Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice

4. JAKS AND STATS: Biological Implications

5. JAK-STAT Signaling: From Interferons to Cytokines

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