4-Substituted-8-(1-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of highly selective GlyT1 inhibitors with superior pharmacological and pharmacokinetic parameters-Reference-Cited by-同舟云学术

4-Substituted-8-(1-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of highly selective GlyT1 inhibitors with superior pharmacological and pharmacokinetic parameters

Published:2006-08 Issue:16 Volume:16 Page:4321-4325
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Alberati Daniela,Hainzl Dominik,Jolidon Synèse,Kurt Anke,Pinard Emmanuel,Thomas Andrew W.,Zimmerli Daniel

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. N-Methyl-d-aspartate receptors as a target for improved antipsychotic agents: novel insights and clinical perspectives

2. The Neuropsychopharmacology of Phencyclidine From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia

3. Glycine transporters: essential regulators of neurotransmission

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3. GlyT-1 Inhibitors: From Hits to Clinical Candidates;Small Molecule Therapeutics for Schizophrenia;2014

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5. An overview of Glyt-1 inhibitors under evaluation for the treatment of schizophrenia;Drugs of the Future;2013