β-Secretase inhibitors: Modification at the P4 position and improvement of inhibitory activity in cultured cells-Reference-Cited by-同舟云学术

β-Secretase inhibitors: Modification at the P4 position and improvement of inhibitory activity in cultured cells

Published:2006-08 Issue:16 Volume:16 Page:4354-4359
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hamada Yoshio,Igawa Naoto,Ikari Hayato,Ziora Zyta,Nguyen Jeffrey-Tri,Yamani Abdellah,Hidaka Koushi,Kimura Tooru,Saito Kazuki,Hayashi Yoshio,Ebina Maiko,Ishiura Shoichi,Kiso Yoshiaki

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Structure of the Protease Domain of Memapsin 2 (β-Secretase) Complexed with Inhibitor

2. AMYLOIDOSIS

3. Toward a Comprehensive Theory for Alzheimer's Disease. Hypothesis: Alzheimer's Disease Is Caused by the Cerebral Accumulation and Cytotoxicity of Amyloid β-Protein

4. Genes and mechanisms involved in β-amyloid generation and Alzheimer's disease

5. The Deposition of Amyloid Proteins in the Aging Mammalian Brain: Implications for Alzheimer's Disease

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