Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold-Reference-Cited by-同舟云学术

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Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold

Published:2015-10 Issue:19 Volume:25 Page:4250-4253
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Leiva Rosana,Seira Constantí,McBride Andrew,Binnie Margaret,Luque F. Javier,Bidon-Chanal Axel,Webster Scott P.,Vázquez Santiago

Funder

Ministerio de Educación, Cultura y Deporte

Ministerio de Economía y Competitividad

Generalitat de Catalunya

ACCIÓ

CIDQO 2012 SL

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

1. Use of the Adamantane Structure in Medicinal Chemistry

2. The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives

3. Are the 2-Isomers of the Drug Rimantadine Active Anti-Influenza a Agents?

4. Structure–Activity Relationships and Optimization of 3,5-Dichloropyridine Derivatives As Novel P2X7Receptor Antagonists

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. N-(1-ADAMANTYLCARBAMOTHIOYL)BENZAMIDES: SYNTHESIS, BIOLOGICAL EVALUATION AND ADME PREDICTIONS;FARMACIA;2018-12-22

2. Exploring N-acyl-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-enes as 11β-HSD1 Inhibitors;Molecules;2018-02-28

3. Design, synthesis and in vivo study of novel pyrrolidine-based 11β-HSD1 inhibitors for age-related cognitive dysfunction;European Journal of Medicinal Chemistry;2017-10

4. Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors;Bioorganic & Medicinal Chemistry;2015-12

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