Trimethylsilylpyrazoles as novel inhibitors of p38 MAP kinase: A new use of silicon bioisosteres in medicinal chemistry-Reference-Cited by-同舟云学术

Trimethylsilylpyrazoles as novel inhibitors of p38 MAP kinase: A new use of silicon bioisosteres in medicinal chemistry

Published:2007-01 Issue:2 Volume:17 Page:354-357
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Barnes Matthew J.,Conroy Richard,Miller David J.,Mills John S.,Montana John G.,Pooni Parminder K.,Showell Graham A.,Walsh Louise M.,Warneck Julie B.H.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. Chemistry challenges in lead optimization: silicon isosteres in drug discovery

2. p38 MAP kinase: a convergence point in cancer therapy

3. The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

Cited by 59 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Nickel-catalyzed cross-electrophile couplings of aryl fluorosulfates with vinyl chlorosilanes;Journal of Catalysis;2024-09

2. The role of silicon in drug discovery: a review;RSC Medicinal Chemistry;2024

3. NBE-Controlled Palladium-Catalyzed Intermolecular Selective C–H Silylation of Boronic Acids;The Journal of Organic Chemistry;2023-10-03

4. Investigation of cytotoxic properties of some isoindole-related compounds bearing silyl and azide groups with in vitro and in silico studies;Phosphorus, Sulfur, and Silicon and the Related Elements;2023-07-12

5. Electrochemical Silylation of Electron‐Deficient Heterocycles Using N‐Hydroxyphthalimide as HAT Catalyst;Advanced Synthesis & Catalysis;2023-04-03