Discovery of γ-secretase inhibitors efficacious in a transgenic animal model of Alzheimer’s disease-Reference-Cited by-同舟云学术

Discovery of γ-secretase inhibitors efficacious in a transgenic animal model of Alzheimer’s disease

Published:2007-01 Issue:2 Volume:17 Page:511-516
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Asberom Theodros,Zhao Zhiqiang,Bara Thomas A.,Clader John W.,Greenlee William J.,Hyde Lynn A.,Josien Hubert B.,Li Wei,McPhail Andrew T.,Nomeir Amin A.,Parker Eric M.,Rajagopalan Murali,Song Lixin,Wong Gwendolyn T.,Zhang Lili,Zhang Qi,Pissarnitski Dmitri A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference10 articles.

1. Deaths attributable to Alzheimer's disease in the United States.

2. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

3. Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

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