Discovery of novel hydroxamates as highly potent tumor necrosis factor-α converting enzyme inhibitors. Part II: Optimization of the S3′ pocket-Reference-Cited by-同舟云学术

Discovery of novel hydroxamates as highly potent tumor necrosis factor-α converting enzyme inhibitors. Part II: Optimization of the S3′ pocket

Published:2008-11 Issue:21 Volume:18 Page:5809-5814
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Mazzola Robert D.,Zhu Zhaoning,Sinning Lisa,McKittrick Brian,Lavey Brian,Spitler James,Kozlowski Joseph,Neng-Yang Shih,Zhou Guowei,Guo Zhuyan,Orth Peter,Madison Vincent,Sun Jing,Lundell Daniel,Niu Xiaoda

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. Adamalysins: A Family of Metzincins Including TNF-alpha Converting Enzyme (TACE)

2. A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF

3. A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

4. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

5. Anti-TNF agents in Crohn’s disease

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Biomolecular interactions between the antibacterial ceftolozane and the human inflammatory disease target ADAM17: a drug repurposing study;Journal of Biomolecular Structure and Dynamics;2023-10-05

2. The discovery of potential tumor necrosis factor alpha converting enzyme inhibitors via implementation of K Nearest Neighbor QSAR analysis;Pharmacia;2023-04-12

3. Selection of Suitable Protein Structure from Protein Data Bank: An Important Step in Structure-based Drug Design Studies;Mini-Reviews in Medicinal Chemistry;2023-02

4. In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators;International Journal of Molecular Sciences;2022-01-25

5. Vitamin D3 Prevents the Deleterious Effects of Testicular Torsion on Testis by Targeting miRNA-145 and ADAM17: In Silico and In Vivo Study;Pharmaceuticals;2021-11-25