Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands

Published:2015-05 Issue:9 Volume:25 Page:1880-1883
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Yang Zhi-Heng,Bai Xiao-Guang,Zhou Lei,Wang Ju-Xian,Liu Hong-Tao,Wang Yu-Cheng

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. HIV-1 protease and reverse transcriptase mutations for drug resistance surveillance

2. Molecular basis of human immunodeficiency virus drug resistance: An update

3. New Disease Baffles Medical Community

4. Joint United Nations Programme on HIV/AIDS. Global Report: UNAIDS Report on the Global AIDS Epidemic 2013; UNAIDS/WHO: Geneva.

5. Selective and facile assay of human immunodeficiency virus protease activity by a novel fluorogenic reaction

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, Synthesis and X‐Ray Structural Studies of Potent HIV‐1 Protease Inhibitors Containing C‐4 Substituted Tricyclic Hexahydro‐Furofuran Derivatives as P2 Ligands;ChemMedChem;2022-03-04

2. Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance;Chemical Communications;2022

3. The Pseudo-Symmetric N-benzyl Hydroxyethylamine Core in a New Series of Heteroarylcarboxyamide HIV-1 Pr Inhibitors: Synthesis, Molecular Modeling and Biological Evaluation;Biomolecules;2021-10-26

4. Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study;PLOS ONE;2020-07-22

5. Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies;Journal of Medicinal Chemistry;2020-04-29

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