Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1′-P2′ ligands-Reference-Cited by-同舟云学术

Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1′-P2′ ligands

Published:2017-11 Issue:21 Volume:27 Page:4925-4931
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ghosh Arun K.,Sean Fyvie W.,Brindisi Margherita,Steffey Melinda,Agniswamy Johnson,Wang Yuan-Fang,Aoki Manabu,Amano Masayuki,Weber Irene T.,Mitsuya Hiroaki

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

1. Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS

2. Development of Protease Inhibitors and the Fight with Drug‐Resistant HIV‐1 Variants

3. Demonstration of Sustained Drug-Resistant Human Immunodeficiency Virus Type 1 Lineages Circulating among Treatment-Naïve Individuals

4. Prevention of HIV-1 Infection with Early Antiretroviral Therapy

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